The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC - ScienceDirect
NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Le
Aptinyx Receives FDA Fast Track Designation for Development of NYX-2925 as Treatment for Neuropathic Pain Associated with Diabetic Peripheral Neuropathy
NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor - Bowers - 2020 - Journal of Neurochemistry - Wiley Online Library
Negative Readouts: Updates on an NMDAR PAM, an MK2 inhibitor, and a Porcupine inhibitor - Drug Hunter
NYX-2925 | CAS#:2012536-16-0 | Chemsrc
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Aptinyx leaves investors nursing a painful hangover | Evaluate
Aptinyx's Chronic Pain Candidate Fails To Top Placebo In Mid-Stage Study
PDF] NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory | Semantic Scholar
The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC - ScienceDirect
NYX-2925 Is a Novel N-Methyl-d-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat Models of Neuropathic Pain | Journal of Pharmacology and Experimental Therapeutics
Robust Analgesic Activity of Aptinyx's NYX-2925 in Advanced DPN Patients Revealed Through Further Analysis of Data from Phase 2 Study
NYX-2925 Is a Novel N-Methyl-d-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat Models of Neuropathic Pain | Journal of Pharmacology and Experimental Therapeutics
NYX-2925, A NOVEL, NON-OPIOID, SMALL-MOLECULE MODULATOR OF THE N-METHYL-d-ASPARTATE RECEPTOR (NMDAR), DEMONSTRATES POTENTIAL TO TREAT CHRONIC, SUPRASPINAL CENTRALIZED PAIN CONDITIONS - ScienceDirect
Aptinyx Reopens Enrollment in Fibromyalgia Phase 2 Trial of NYX-2925
Aptinyx stock slumps 34% as musculoskeletal pain drug NYX-2925 fails mid-stage study | Seeking Alpha
Figure 1 from NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory | Semantic Scholar
Aptinyx-raises-funds-neurologic-drugs
NYX-2925 Is a Novel N-Methyl-d-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat Models of Neuropathic Pain | Journal of Pharmacology and Experimental Therapeutics
NYX-2925 facilitates the amplitude and phase transition timing of... | Download Scientific Diagram
Aptinyx's NYX-2925 Draws Skepticism As It Fails Another Trial :: Scrip
Aptinyx resumes trial of NYX-2925 for diabetic peripheral neuropathy
Aptinyx Recommences Patient Recruitment in Phase 2 Study of NYX-2925 in Patients with Fibromyalgia
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NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Le